发明名称 Dual-targeted therapeutic peptide for nasopharyngeal carcinoma, nanoparticles carrying same and uses thereof
摘要 Disclosed is a dual-targeted therapeutic peptide for nasopharyngeal carcinoma formed by covalently linking a targeted therapeutic peptide for nasopharyngeal carcinoma, a peptide linker and a targeted therapeutic peptide with an α-helical structure for nasopharyngeal carcinoma. Also disclosed is a nanoparticle containing the peptide. The peptide and the nanoparticle can be used to treat nasopharyngeal carcinoma.
申请公布号 US9371364(B2) 申请公布日期 2016.06.21
申请号 US201314406399 申请日期 2013.06.07
申请人 HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY 发明人 Luo Qingming;Zhang Zhihong;Luo Haiming
分类号 A61K38/16;C07K14/00;C07K7/08;A61K9/51;A61K31/12;A61K31/337;C07K14/47;A61K47/48;A61K49/00;A61K38/10;A61K47/42 主分类号 A61K38/16
代理机构 Carter, DeLuca, Farrell & Schmidt, LLP 代理人 Carter, DeLuca, Farrell & Schmidt, LLP
主权项 1. A peptide for nasopharyngeal carcinoma, wherein the peptide for nasopharyngeal carcinoma is formed by covalently linking FAEKFKEAVKDYFAKFWD (SEQ ID NO:2), a peptide linker and LTVSPWYLTVSPWY (SEQ ID NO:3) in sequence.
地址 Wuhan, Hubei CN