发明名称 |
Dual-targeted therapeutic peptide for nasopharyngeal carcinoma, nanoparticles carrying same and uses thereof |
摘要 |
Disclosed is a dual-targeted therapeutic peptide for nasopharyngeal carcinoma formed by covalently linking a targeted therapeutic peptide for nasopharyngeal carcinoma, a peptide linker and a targeted therapeutic peptide with an α-helical structure for nasopharyngeal carcinoma. Also disclosed is a nanoparticle containing the peptide. The peptide and the nanoparticle can be used to treat nasopharyngeal carcinoma. |
申请公布号 |
US9371364(B2) |
申请公布日期 |
2016.06.21 |
申请号 |
US201314406399 |
申请日期 |
2013.06.07 |
申请人 |
HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY |
发明人 |
Luo Qingming;Zhang Zhihong;Luo Haiming |
分类号 |
A61K38/16;C07K14/00;C07K7/08;A61K9/51;A61K31/12;A61K31/337;C07K14/47;A61K47/48;A61K49/00;A61K38/10;A61K47/42 |
主分类号 |
A61K38/16 |
代理机构 |
Carter, DeLuca, Farrell & Schmidt, LLP |
代理人 |
Carter, DeLuca, Farrell & Schmidt, LLP |
主权项 |
1. A peptide for nasopharyngeal carcinoma, wherein the peptide for nasopharyngeal carcinoma is formed by covalently linking FAEKFKEAVKDYFAKFWD (SEQ ID NO:2), a peptide linker and LTVSPWYLTVSPWY (SEQ ID NO:3) in sequence. |
地址 |
Wuhan, Hubei CN |