| 摘要 |
The present invention provides, for example, a compound of the following formula (I): 1
wherein R 1 is substituted amino and the like,
R 2 is halogen and the like,
R 3 is substituted or unsubstituted lower alkyl and the like,
R A and R B are each independently hydrogen, substituted or unsubstituted lower alkyl and the like,
R C and R D are each independently hydrogen, substituted or unsubstituted lower alkyl, or R C and R D together with the carbon atom to which they are attached may form a substituted or unsubstituted carbocycle, and
ring A is a carbocycle or a heterocycle,
its pharmaceutically acceptable salt, or a solvate thereof as a therapeutic agent for diseases induced by production, secretion and/or deposition of amyloid-² proteins. |
