| 发明名称 |
BIS- (SULF ONYLAMINO) DERIVATIVES FOR USE IN THERAPY |
| 摘要 |
<p>The invention provides compounds of formula (I) wherein R1, R3, L1, L2, G1, G2, A and m are as defined in the specification and optical isomers, racemates and tautomers thereof, and pharmaceutically acceptable salts thereof; together with processes for their preparation, pharmaceutical compositions containing them and their use in therapy. The compounds are inhibitors of microsomal prostaglandin E synthase-1.</p> |
| 申请公布号 |
EP2234993(A4) |
申请公布日期 |
2012.02.08 |
| 申请号 |
EP20080863493 |
申请日期 |
2008.12.18 |
| 申请人 |
ASTRAZENECA AB |
发明人 |
BYLUND, JOHAN;EK, MARIA E;GRAVENFORS, YLVA;HOLENZ, JOERG;MINIDIS, ALEXANDER;NORDVALL, GUNNAR;SOHN, DANIEL;VALLIN, KARL S.A;VIKLUND, JENNY;VON BERG, STEFAN |
| 分类号 |
C07D307/79;A61K31/18;A61K31/341;A61K31/343;A61K31/381;A61K31/404;A61K31/4155;A61K31/4245;A61K31/426;A61K31/4402;A61K31/4418;A61K31/505;A61P29/00;C07C311/44;C07D209/10;C07D213/30;C07D213/64;C07D233/96;C07D271/10;C07D277/32;C07D307/10 |
主分类号 |
C07D307/79 |
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