发明名称 CD20特異的抗体およびその使用方法
摘要 The present invention provides monoclonal antibodies and antigen-binding fragments thereof that specifically bind to CD20, as well as pharmaceutical compositions comprising the same. The invention further provides methods of using the monoclonal antibodies, antigen-binding fragments, and pharmaceutical compositions, for example, in methods of depleting B-cells or in treating B-cell disorders. Also provided are cells, nucleic acids and methods for producing the monoclonal antibodies.
申请公布号 JP5969577(B2) 申请公布日期 2016.08.17
申请号 JP20140236224 申请日期 2014.11.21
申请人 デューク ユニバーシティ 发明人 トーマス エフ. テッダー;内田 純二;濱口 儒人;ジョナサン シー. ポー
分类号 C07K16/28;A61K39/395;A61K45/00;A61K45/06;A61K49/00;A61K51/00;A61P1/04;A61P3/10;A61P5/14;A61P7/06;A61P9/00;A61P17/00;A61P17/02;A61P17/06;A61P19/02;A61P21/00;A61P21/04;A61P25/00;A61P27/02;A61P29/00;A61P35/00;A61P35/02;C07K16/46;C12N5/20;C12N15/13 主分类号 C07K16/28
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