发明名称 |
3 ARYL OR HETEROARYL-SUBSTITUTED INDOLE DERIVATIVE |
摘要 |
A 3-aryl or heteroaryl-substituted indole derivative which is effective as a preventive or remedy for various diseases is provided. [Means for Resolution] A compound represented by a formula (I) or a pharmaceutically acceptable salt thereof is provided. In the formula, R1 represents a hydrogen atom, C1-6 alkyl et al; R2 represents a hydrogen atom, C1-6 alkyl et al; Z represents aryl or heteroaryl (with the proviso that imidazolyl is excluded); and W represents a group represented by the formula (w-1) or (w-2). In the formula, R3 represents C1-6 alkyl et al; Yl and Y2 both represent a hydrogen atom or Y1 and Y2 together form —CH2-CH2-; Q represents CH or N; Ar represents phenyl, furyl et al; R4 and R5 each independently represent a hydrogen atom or C1-6 alkyl or R4 and R5 together with the nitrogen atom form pyrrolidine et al. |
申请公布号 |
US2012028990(A1) |
申请公布日期 |
2012.02.02 |
申请号 |
US201013260746 |
申请日期 |
2010.04.14 |
申请人 |
FUJIMURA TAKASHI;KISHINO HIROYUKI;MIZUTANI TAKASHI;SAKURABA SHUNJI;SASAKI TAKAHIDE;SATO NAGAAKI;MSD K.K |
发明人 |
FUJIMURA TAKASHI;KISHINO HIROYUKI;MIZUTANI TAKASHI;SAKURABA SHUNJI;SASAKI TAKAHIDE;SATO NAGAAKI |
分类号 |
A61K31/404;A61K31/4439;A61K31/454;A61K31/4725;A61K31/496;A61P3/04;C07D403/12;C07D405/14;C07D409/14;C07D417/14 |
主分类号 |
A61K31/404 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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