发明名称 METHOD AND MEANS FOR CURING OSTEOARTHRITIS
摘要 <P>PROBLEM TO BE SOLVED: To provide a method for identifying a compound for guiding an assimilation stimulant action of chondrocytic cells. <P>SOLUTION: The method includes steps of: bringing the compound into contact with polypeptide containing an amino acid sequence to be selected from a group consisting of sequence numbers 58 and 59; and measuring characteristics of compound-polypeptide relevant to the assimilation stimulant action of the chondrocytic cells. In the method, the characteristics include coupling affinities of the compound to the polypeptide, and activation of a biological path for producing a biochemical marker to be an index of the assimilation stimulant action of the chondrocytic cells. <P>COPYRIGHT: (C)2012,JPO&INPIT
申请公布号 JP2012021995(A) 申请公布日期 2012.02.02
申请号 JP20110171061 申请日期 2011.08.04
申请人 GALAPAGOS NV 发明人 NICK VANDEGINSTE;PETER HELWIG MARIA TOME;FRITZ MICHAEL;LIBIN MA;BRANDINI MILLERET BAKEL;HELMS HG VERNEST
分类号 G01N33/50;A61K38/17;C12N15/09;C12N15/11;C12Q1/02;C12Q1/68;G01N33/15;G01N33/566;G01N33/68 主分类号 G01N33/50
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