发明名称 |
CD49F PROMOTING PROLIFERATION, MULTIPOTENCY AND REPROGRAMMING OF ADULT STEM CELLS THROUGH PI3K/AKT/GSK3 PATHWAY |
摘要 |
The present invention relates to a method for obtaining adult stem cells, which have a surface antigen of CD49f, excellent formation of spheres due to sphere formation and high expression of OCT4 and SOX2, from a cell source including stem cells, and a cell therapeutic agent containing adult stem cells obtained by the method or cells differentiated therefrom as an active ingredient. According to the present invention, adult stem cells derived from spheres are suitable for mass culture of adult stem cells because of more rapid growth thereof compared with stem cells obtained by a known adhesion culture method, have a specific surface antigen so as to be homogeneously obtained by using the specific surface antigen, and are useful for preparing a cell therapeutic agent using the same because of excellent differentiation thereof. |
申请公布号 |
WO2011102680(A3) |
申请公布日期 |
2012.02.02 |
申请号 |
WO2011KR01103 |
申请日期 |
2011.02.18 |
申请人 |
KANG STEM HOLDINGS CO., LTD;KANG, KYUNG SUN;YU, KYUNG ROK |
发明人 |
KANG, KYUNG SUN;YU, KYUNG ROK |
分类号 |
C12N5/074;A61K35/12;C12Q1/24;G01N33/53 |
主分类号 |
C12N5/074 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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