发明名称 |
Pyrazolopyrimidine JAK inhibitor compounds and methods |
摘要 |
<p>A compound of Formula I, enantiomers, diasteriomers, tautomers or pharmaceutically acceptable salts thereof, wherein R, R and R are defined herein, are useful as inhibitors of one or more Janus kinases. A pharmaceutical composition that includes a compound of Formula I and a pharmaceutically acceptable carrier, adjuvant or vehicle, and methods of treating or lessening the severity of a disease or condition responsive to the inhibition of a Janus kinase activity in a patient are disclosed.</p> |
申请公布号 |
AU2010266188(A1) |
申请公布日期 |
2012.02.02 |
申请号 |
AU20100266188 |
申请日期 |
2010.07.02 |
申请人 |
GENENTECH, INC. |
发明人 |
GIBBONS, PAUL;HANAN, EMILY;LIU, WENDY;LYSSIKATOS, JOSEPH P.;MAGNUSON, STEVEN R.;MENDONCA, ROHAN;PASTOR, RICHARD;RAWSON, THOMAS E.;SIU, MICHAEL;ZAK, MARK E.;ZHOU, AIHE;ZHU, BING-YAN |
分类号 |
C07D487/04;A61K31/437;A61P35/00;C07D403/12 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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