发明名称 Pyrazolopyrimidine JAK inhibitor compounds and methods
摘要 <p>A compound of Formula I, enantiomers, diasteriomers, tautomers or pharmaceutically acceptable salts thereof, wherein R, R and R are defined herein, are useful as inhibitors of one or more Janus kinases. A pharmaceutical composition that includes a compound of Formula I and a pharmaceutically acceptable carrier, adjuvant or vehicle, and methods of treating or lessening the severity of a disease or condition responsive to the inhibition of a Janus kinase activity in a patient are disclosed.</p>
申请公布号 AU2010266188(A1) 申请公布日期 2012.02.02
申请号 AU20100266188 申请日期 2010.07.02
申请人 GENENTECH, INC. 发明人 GIBBONS, PAUL;HANAN, EMILY;LIU, WENDY;LYSSIKATOS, JOSEPH P.;MAGNUSON, STEVEN R.;MENDONCA, ROHAN;PASTOR, RICHARD;RAWSON, THOMAS E.;SIU, MICHAEL;ZAK, MARK E.;ZHOU, AIHE;ZHU, BING-YAN
分类号 C07D487/04;A61K31/437;A61P35/00;C07D403/12 主分类号 C07D487/04
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