发明名称 |
COMPOSITIONS FOR TREATING OR PREVENTING OBESITY AND INSULIN RESISTANCE DISORDERS |
摘要 |
Provided herein are methods and compositions for modulating the activity or level of a sirtuin, thereby treating or preventing obesity or an insulin resistance disorder, such as diabetes in a subject. Exemplary methods comprise contacting a cell with a sirtuin activating compound or an inhibitory compound to thereby increase or decrease fat accumulation, respectively.
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申请公布号 |
US2012029065(A1) |
申请公布日期 |
2012.02.02 |
申请号 |
US201113192011 |
申请日期 |
2011.07.27 |
申请人 |
SINCLAIR DAVID A.;ALEXANDER-BRIDGES MARIA;THE GENERAL HOSPITAL CORPORATION D/B/A MASSACHUSETTS GENERAL HOSPITAL;PRESIDENT AND FELLOWS OF HARVARD COLLEGE |
发明人 |
SINCLAIR DAVID A.;ALEXANDER-BRIDGES MARIA |
分类号 |
A61K31/352;A61K31/05;A61K31/12;A61K31/353;A61K31/7048;A61P3/00;A61P3/04;A61P3/10 |
主分类号 |
A61K31/352 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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