发明名称 |
TARGETING PULMONARY EPITHELIUM USING ADRP |
摘要 |
This invention provides novel compositions and methods for the specific and/or preferential delivery of an effector (e.g. a drug or label) to an epithelial cell (e.g. a pulmonary epithelium). The compositions comprise an adipocyte differentiation-related protein (ADRP) attached to an effector thereby forming a chimeric moiety. The chimeric moiety is preferentially delivered to epithelial cells. |
申请公布号 |
US2012027675(A1) |
申请公布日期 |
2012.02.02 |
申请号 |
US201113276204 |
申请日期 |
2011.10.18 |
申请人 |
TORDAY JOHN S.;REHAN VIRENDER K.;LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT HARBOR-UCLA MEDICAL CENTER |
发明人 |
TORDAY JOHN S.;REHAN VIRENDER K. |
分类号 |
A61K51/00;A61K9/127;A61K38/00;A61K49/00;A61P35/00;C12N5/02 |
主分类号 |
A61K51/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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