GLP-1 RECEPTOR AGONIST COMPOUNDS HAVING STABILIZED REGIONS
摘要
<p>The disclosure provides GLP-1 receptor agonist compounds having stabilized regions corresponding to alpha-helical regions of the natural peptide compounds. The disclosure also provides benzamide-containing exendin-4 analogs and alkene-constrained exendin-4 analogs, both of which have stabilized regions corresponding to alpha-helical regions of exendin-4.</p>
申请公布号
WO2012015975(A2)
申请公布日期
2012.02.02
申请号
WO2011US45614
申请日期
2011.07.27
申请人
AMYLIN PHARMACEUTICALS, INC.;ALFARO-LOPEZ, JOSUE;SHARMA, ABHINANDINI;SOARES, CHRISTOPHER, J.;COATS, EUGENE;GHOSH, SOUMITRA, S.
发明人
ALFARO-LOPEZ, JOSUE;SHARMA, ABHINANDINI;SOARES, CHRISTOPHER, J.;COATS, EUGENE;GHOSH, SOUMITRA, S.
