发明名称 |
HIGHLY POTENT PEPTIDES TO CONTROL CANCER AND NEURODEGENERATIVE DISEASES |
摘要 |
This invention provides compositions and method of diminishing or inhibiting autophagy by administering a FLIP protein that binds to Atg3, interfering with the formation of the LC3-Atg4-Atg7-Atg3 conjugation complex necessary for autophagy induction. This invention also provides FLIP peptide fragments that promote or induce autophagy by interfering with the activity of FLIP. |
申请公布号 |
WO2012015836(A1) |
申请公布日期 |
2012.02.02 |
申请号 |
WO2011US45406 |
申请日期 |
2011.07.26 |
申请人 |
UNIVERSITY OF SOUTHERN CALIFORNIA;JUNG, JAE U. |
发明人 |
JUNG, JAE U. |
分类号 |
A61K38/08;A61K38/10;C07K7/06;C07K7/08 |
主分类号 |
A61K38/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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