发明名称 |
NOVEL RET FUSED BODY DETECTION METHOD |
摘要 |
<p>Disclosed is a method which elucidates polynucleotides which are new cancer-causing genes, and thus detects the polynucleotides, or polypeptides which the polynucleotides code. Also disclosed are a kit and a primer set for the detection method. It has been found that a fusion gene which is formed of part of a KIF5B gene and part of an RET gene, and is present in part of a cancer patient is a cancer-causing gene, and a method for detecting polynucleotides, which are said gene, and polypeptides, which the polynucleotides code, has been formulated. In the method, the fusion gene formed of part of a KIF5B gene and part of an RET gene, or the fusion protein which the gene codes is detected. The primer set and the kit for detection include a sense primer which is designed from a portion which codes KIF5B, and an anti-sense primer which is designed from a portion which codes RET.</p> |
申请公布号 |
WO2012014795(A1) |
申请公布日期 |
2012.02.02 |
申请号 |
WO2011JP66661 |
申请日期 |
2011.07.22 |
申请人 |
ASTELLAS PHARMA INC.;SHINDO, NOBUAKI;NISHIMURA, KOUICHI;SANO, YORIKATA;ASAUMI, MAKOTO;TAKEHANA, AYA;FUTAMI, TAKASHI;KAWASE, TATSUYA |
发明人 |
SHINDO, NOBUAKI;NISHIMURA, KOUICHI;SANO, YORIKATA;ASAUMI, MAKOTO;TAKEHANA, AYA;FUTAMI, TAKASHI;KAWASE, TATSUYA |
分类号 |
C12Q1/68;C12N15/09;G01N33/58 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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