| 发明名称 |
METHOD FOR AMELIORATING PAIN BY MODIFICATION OF NMDA RECEPTORS THROUGH INHIBITION OF SRC |
| 摘要 |
The present invention provides a method for ameliorating inflammatory and/or neuropathic pain in a subject by modifying the activity of N-methyl-D-aspartate (NMDA) receptors in cells of the subject by inhibition of the interaction of the unique domain of the tyrosine kinase Src enzyme and the NMDA receptor complex.
|
| 申请公布号 |
US2012029168(A1) |
申请公布日期 |
2012.02.02 |
| 申请号 |
US201113165764 |
申请日期 |
2011.06.21 |
| 申请人 |
SALTER MICHAEL W.;GINGRICH JEFFREY R.;THE HOSPITAL FOR SICK CHILDREN |
发明人 |
SALTER MICHAEL W.;GINGRICH JEFFREY R. |
| 分类号 |
C07K14/435;A61K38/00;A61K38/08;A61K38/10;A61K38/17;C07K7/08;C07K14/16;C12N9/02 |
主分类号 |
C07K14/435 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
