发明名称 |
NOVEL COMPOUNDS FUSARISETINS AND USES THEREOF |
摘要 |
PURPOSE: A novel fusarisetin compound isolated from Fusarium sp. fungus FN080326 is provided to suppress proliferation of cancer cells such as liver cancer cells, breast cancer cells, and myeloid leukemia cells. CONSTITUTION: A novel fusarisetin compound is denoted by chemical formula 1. A fusarisetin A compound is denoted by chemical formula 2 or 3. The fusarisetin compound is isolated from Fusarium sp. FN08026. A pharmaceutical composition for preventing and treating cancer contains the fusarisetin compound or pharmaceutically acceptable salt threreof as an active ingredient. A method for preparing the fusarisetin compound comprises: a step of culturing Fusarium sp. FN080326; and a step of isolating the fusarisetin compound from strain culture. |
申请公布号 |
KR20120010175(A) |
申请公布日期 |
2012.02.02 |
申请号 |
KR20110072017 |
申请日期 |
2011.07.20 |
申请人 |
KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY |
发明人 |
AHN, JONG SEOG;JANG, JAE HYUK;KIM, BO YEON;JANG, JUN PHIL;ASAMI YUKIHIRO;OH, HYUN CHEOL |
分类号 |
C07D491/048;A61K31/407;A61P35/00 |
主分类号 |
C07D491/048 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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