| 发明名称 |
INHIBITION OF CYP3A DRUG METABOLISM |
| 摘要 |
The present invention provides methods, pharmaceutical compositions, medicaments, and pharmaceutical kits that employ the use of boceprevir as a CYP3A4/5 inhibitor to improve the pharmacokinetics of therapeutic compounds metabolized by cytochrome P450 3A4/5 (CYP3A4/5) enzymes.
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| 申请公布号 |
CA2805760(A1) |
申请公布日期 |
2012.02.02 |
| 申请号 |
CA20112805760 |
申请日期 |
2011.07.25 |
| 申请人 |
MERCK SHARP & DOHME CORP. |
发明人 |
GHOSAL, ANIMA;GUPTA, SAMIR;KISHNANI, NARENDRA;KASSERRA, CLAUDIA;O'MARA, EDWARD |
| 分类号 |
A61K38/06;A61K31/46;A61K31/503;A61K31/506;A61K31/519;A61K38/08;A61P31/12 |
主分类号 |
A61K38/06 |
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