发明名称 |
MATRIX-TYPE SUSTAINED RELEASE PREPARATION CONTAINING BASIC ADDITIVE |
摘要 |
<p>Disclosed is a matrix-type sustained release preparation containing a basic drug unstable against an acid as an active pharmaceutical ingredient, wherein the decomposition of the basic drug unstable against the acid can be prevented and therefore the pH-dependent release can be reduced. A hardly water-soluble basic normal salt is added to a matrix-type sustained release preparation containing a basic drug that is unstable against an acid.</p> |
申请公布号 |
EP2412370(A1) |
申请公布日期 |
2012.02.01 |
申请号 |
EP20100756232 |
申请日期 |
2010.03.26 |
申请人 |
KYORIN PHARMACEUTICAL CO., LTD. |
发明人 |
FUKUDA MAMORU;TAKAHASHI MAYUKO;GOTO TAKAHIRO |
分类号 |
A61K31/40;A61K9/20;A61K9/22;A61K31/403;A61K31/4196;A61K47/02;A61K47/10;A61K47/26 |
主分类号 |
A61K31/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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