发明名称 |
N-[3-FLUORO-4-({6-(METHYLOXY)-7-[(3-MORPHOLIN-4-YLPROPYL)OXY]QUINOLIN-4-YL}OXY)PHENYL]-N`-(4-FLUOROPHENYL)CYCLOPROPANE-1,1-DICARBOXAMIDE FOR THE TREATMENT OF CANCER |
摘要 |
The present invention provides a compound which is represented by the following structure:
which inhibits, regulates and/or modulates kinase receptors, particularly c-Met, KDR, c-Kit, flt-3 and flt-4. This compound is therefore suitable for the treatment of diseases or disorders associated with uncontrolled, abnormal and/or unwanted cellular activities. |
申请公布号 |
PT2210607(E) |
申请公布日期 |
2012.01.31 |
申请号 |
PT20100160517T |
申请日期 |
2004.09.24 |
申请人 |
EXELIXIS INC. |
发明人 |
JOHN M. NUSS;WEI XU;LYNNE CANNE BANNEN;DIVA SZE-MING CHAN;TIMOTHY PATRICK FORSYTH;RICHARD GEORGE KHOURY;JAMES WILLIAM LEAHY;MORRISON B. MAC;LARRY W. MANN;JASON JEVIOUS PARKS;YONG WANG;JEFF CHEN;LISA ESTHER DALRYMPLE;TAI PHAT HUYNH;VASU JAMMALAMADAKA;GRACE MANN;CRAIG STACY TAKEUCHI |
分类号 |
A61K31/47;A61K;A61K31/535;A61P35/00;C07D215/16;C07D215/20;C07D215/22;C07D413/00 |
主分类号 |
A61K31/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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