| 发明名称 |
METHODS AND REAGENTS FOR EFFICIENT AND TARGETED GENE TRANSFER TO MONOCYTES AND MACROPHAGES |
| 摘要 |
<p>The present invention provides a biosafe and useful vector to transfer genetic material to CD14+ mononuclear cells (monocytcs and monocytc-dcrivcd macrophagcs) in an efficient and specific manner. The embodiment of the invention makes use of the chimeric human adenovirus vectors 5 carrying the short fiber of enterotropic Ad40 to transfer genetic material to the target CD14+ mononuclear cells.</p> |
| 申请公布号 |
IL215688(D0) |
申请公布日期 |
2012.01.31 |
| 申请号 |
IL20110215688 |
申请日期 |
2011.10.11 |
| 申请人 |
FUNDACIO PRIVADA INSTITUCIO CATALANA DE RECERCA IESTUDIS AVANCATS;UNIVERSITAT AUTONOMA DE BARCELONA;GRIFOLS, S.A;FUNDACIO INSTITUT D'INVESTIGACIO EN CIENCIES DE LA SALUT GERMANS TRIAS I PUJOL OF |
发明人 |
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| 分类号 |
C12N |
主分类号 |
C12N |
| 代理机构 |
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| 主权项 |
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