发明名称 |
ATTENUATED FLAVIVIRAL LIVE VACCINE COMPRISING A CAPSID PROTEIN DELETION |
摘要 |
Disclosed is an attenuated flavivirus live vaccine comprising a flavivirus mutant, characterised in that the flavivirus mutant has a deletion in the capsid protein of at least more than 4 suc-cessive amino acids, wherein the carboxy-terminal hydrophobic re-gion is not affected by the deletion.
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申请公布号 |
CA2432370(C) |
申请公布日期 |
2012.01.31 |
申请号 |
CA20022432370 |
申请日期 |
2002.02.11 |
申请人 |
HEINZ, FRANZ X.;MANDL, CHRISTIAN |
发明人 |
HEINZ, FRANZ X.;MANDL, CHRISTIAN |
分类号 |
C12N7/04;C12N15/09;A61K39/00;A61K39/12;A61K39/29;A61P1/16;A61P31/14;C07K14/18;C12N15/40 |
主分类号 |
C12N7/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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