IMPROVED RECONSTITUTED SURFACTANT COMPOSITION CONTAINING ANALOGS OF SURFACTANT PROTEIN B (SP-B) AND SURFACTANT PROTEIN C (SP-C)

摘要

The present invention is directed to a reconstituted pulmonary surfactant comprising a lipid carrier, a combination of polypeptide analog of the native surfactant protein SP-C with a particular polypeptide analog of the native surfactant protein SP-B. The invention is also directed to the pharmaceutical formulations thereof and to its use for the treatment or prophylaxis of RDS and other respiratory disorders.