发明名称 |
PROCESS FOR THE PRODUCTION OF DRONEDARONE INTERMEDIATES |
摘要 |
<p>A process for the production of Dronedarone intermediates of the formula (I), by acylation of 2-(2-hydroxy-5-nitrophenyl)-1-(4-methoxyphenyl)-ethanone, subsequent treatment of the ester with bases and a zeolite (alumosilicate) catalyst and optional subsequent demethylation. This process can be used for the production of Dronedarone.</p> |
申请公布号 |
SG176212(A1) |
申请公布日期 |
2012.01.30 |
申请号 |
SG20110086667 |
申请日期 |
2010.05.26 |
申请人 |
SANOFI |
发明人 |
KRETZSCHMAR, GERHARD;KRAFT, VOLKER;ROSSEN, KAI;GRAESER, JOACHIM |
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