4-ARYLCUMARINE DERIVATIVES AND BASED ONCOLOGY DRUG

摘要

FIELD: medicine, pharmaceutics. ^ SUBSTANCE: present invention refers to 4-arylcumarine derivatives and a based drug which can be used for treating tumours of general formula ^ , where A means a group , where CnHm represents residual fatty acids of saturate and olefin series, n represents number 13, 15 or 17, m represents number 27, 31 or 33, while R1, R2, R3 represent hydrogen atoms and/or methoxygroup OCH3. The drug contains said 4-arylcumarine derivatives contained in liposomes containing phosphatidylcholine, phosphatidylinositol and lipid oligopolysaccharide. ^ EFFECT: there are prepared the new oncology compounds and the new drug showing lesser systemic toxicity and greater membrane affinity. ^ 12 cl, 9 ex, 1 tbl, 3 dwg