SYSTEMS AND METHODS OF PREDICTING A SUBJECT'S MEDICAL OUTCOME

摘要

Disclosed are methods of constructing systems for predicting a subject's medical outcome. Also disclosed are methods and systems for predicting a subject's medical outcome. The disclosed methods and systems can include identifying a group of subjects with the same medical condition and classifying this group of subjects into one or more subgroups. The subgroups are classified based on similarity of medical outcome, using classification and regression trees (CART) to generate a classification tree based on the presence of identifying genetic characteristics. Each node in the classification tree describes the presence of a specific genetic marker and each branch in the classification tree describes a genetic profile that predicts a subject's medical outcome.