MAGNETIC RESONANCE IMAGING CONTRAST AGENT COATED WITH POLYMER HAVING MANNOSE-MODIFIED TERMINAL, AND PREPARATION METHOD THEREOF
摘要
The present invention relates to a magnetic resonance imaging contrast agent surface-coated with a polymer which has high stability in the body and biocompatibility, and more specifically, to a superparamagnetic magnetic resonance imaging contrast agent coated with a polymer having a mannose-modified terminal which can be used for enhancing the contrast of images in lymphography, and a preparation method thereof. The superparamagnetic magnetic resonance imaging contrast agent coated with a polymer having a mannose-modified terminal according to the present invention can provide high stability in the body and biocompatibility and can be used for easy diagnosis of the metastasis of cancer to lymph nodes.
申请公布号
WO2011122770(A3)
申请公布日期
2012.01.26
申请号
WO2011KR01544
申请日期
2011.03.07
申请人
INTRON BIOTECHNOLOGY, INC.;YOON, SEONG JUN;JUN, SOO YOUN;KANG, SANG HYEON;JEONG, YONG YEON;PARK, IN KYU;CHO, CHONG SU;YOO, MI KYONG
发明人
YOON, SEONG JUN;JUN, SOO YOUN;KANG, SANG HYEON;JEONG, YONG YEON;PARK, IN KYU;CHO, CHONG SU;YOO, MI KYONG