Production of Targeted MRI Probes by Biocompatible Coupling of Macromolecules with Charged Nanoparticles

摘要

The present invention relates to the production of marker particles, which are especially useful for target-specific molecular magnetic resonance imaging (MRI), using charged iron oxide nanoparticles and inversely charged peptides covalently linked to macromolecules, which are capable of binding to a specific type of cells.