METHOD FOR PREVENTING DAMAGE TO NUCLEAR MEMBRANE OF SKIN CELL BY ADMINISTERING AMENTOFLAVONE

摘要

Provided are a method for preventing damage to the nuclear membrane of skin cell including administering an effective amount of amentoflavone to a subject and a method for anti-aging including administering an effective amount of amentoflavone to a subject. By controlling the expression of defective lamin A induced by UV radiation or controlling the expression of phosphorylated H2A histone family, member X (H2AX) induced by UV radiation, the disclosed method prevents nuclear membrane damage and thus prevents skin cell damage. Accordingly, a composition containing amentoflavone as an active ingredient may be used as a cosmetic composition or a pharmaceutical composition.