发明名称 |
HEDGEHOG PATHWAY INHIBITORS |
摘要 |
This disclosure generally relates to methods useful for improving, for example, blood vessel density and/or blood vessel patency to a tissue by administration of a hedgehog pathway inhibitor. In certain embodiments, the hedgehog pathway inhibitor is administered with an agent to improve the delivery of the agent to the tissue. In certain embodiments, the tissue comprises tumor tissue. |
申请公布号 |
US2012020876(A1) |
申请公布日期 |
2012.01.26 |
申请号 |
US201013144992 |
申请日期 |
2010.01.22 |
申请人 |
OLIVE KENNETH PAUL;TUVESON DAVID |
发明人 |
OLIVE KENNETH PAUL;TUVESON DAVID |
分类号 |
A61K51/00;A61K31/395;A61K31/4355;A61K31/4418;A61K31/496;A61K31/704;A61K31/7068;A61K49/04;A61K49/10;A61K49/22;A61P9/00;A61P35/00;A61P35/04;C12N5/071;C12N5/079;C12N5/09;G01N33/566 |
主分类号 |
A61K51/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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