ARTIFICIAL CELLULOSOME AND THE USE OF THE SAME FOR ENZYMATIC BREAKDOWN OF RESILIENT SUBSTRATES
摘要
The present invention relates to an in vitro produced, artificial cellulosome for enzymatic breakdown of resilient substrates. In particular, the present invention provides a complex having an increased activity on resilient substrates, such as crystalline cellulose. The in vitro formed complex comprises a backbone scaffold having at least four binding sites capable of binding the enzyme components, whereby at least two of the binding sites have essentially the same binding specificity; and at least three different enzyme components being randomly bound to the at least four binding sites. Method for preparing the complex and uses of the same for enzymatic breakdown of resilient substrates are also provided.
申请公布号
WO2012010295(A1)
申请公布日期
2012.01.26
申请号
WO2011EP03617
申请日期
2011.07.19
申请人
SCHWARZ, WOLFGANG H.;KRAUSS, JAN;ZVERLOV, VLADIMIR V.;HORNBURG, DANIEL;KOECK, DANIELA;SCHULTE, LOUIS-PHILIPP
发明人
SCHWARZ, WOLFGANG H.;KRAUSS, JAN;ZVERLOV, VLADIMIR V.;HORNBURG, DANIEL;KOECK, DANIELA;SCHULTE, LOUIS-PHILIPP