| 发明名称 |
PROCESS FOR THE PREPARATION OF (POLY) AMINOALKYLAMINOACETAMIDE DERIVATIVES OF EPIPODOPHYLLOTOXIN USEFUL FOR THEIR APPLICATIONS IN THERAPEUTICS AS ANTICANCER AGENT |
| 摘要 |
The present invention relates to a new process for the preparation of (poly)aminoalkylaminoacetamide derivatives of epipodophyllotoxin and salts thereof, characterised in that it comprises a step of peptide coupling of 4-amino-4′-demethylepipodophyllotoxin with an amine-containing reactant having protecting groups. |
| 申请公布号 |
US2012022273(A1) |
申请公布日期 |
2012.01.26 |
| 申请号 |
US20080733864 |
申请日期 |
2008.09.23 |
| 申请人 |
GUMINSKI YVES;GROUSSEAUD MARTIAL;IMBERT THIERRY;PIERRE FABRE MEDICAMENT |
发明人 |
GUMINSKI YVES;GROUSSEAUD MARTIAL;IMBERT THIERRY |
| 分类号 |
C07D493/04;C07C269/06;C07C271/22 |
主分类号 |
C07D493/04 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
