发明名称 |
SUSTAINED RELEASE siRNA FOR OCULAR DRUG DELIVERY |
摘要 |
The present invention provides an ocular implant comprising siRNA complexed with a transfection agent selected from the group consisting of cationic lipids and short cell penetration peptides, wherein said complex is associated with a biocompatible polymer. Said biocompatible polymer comprises a polymeric matrix configured to release said complex into the eye of a patient at therapeutic levels for a time sufficient to treat an ocular condition or disease.
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申请公布号 |
US2012022002(A1) |
申请公布日期 |
2012.01.26 |
申请号 |
US201113187117 |
申请日期 |
2011.07.20 |
申请人 |
RIVERS HONGWEN M.;SPADA LON T.;LUU MICHELLE |
发明人 |
RIVERS HONGWEN M.;SPADA LON T.;LUU MICHELLE |
分类号 |
A61K38/02;A61K31/713;A61K38/16;A61P27/02;B29D11/00 |
主分类号 |
A61K38/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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