| 发明名称 |
PHARMACEUTICAL COMBINATION OF 5-FLUOROURACIL AND DERIVATE OF 1,4-DIHYDROPYRIDINE AND ITS USE IN THE TREATMENT OF CANCER |
| 摘要 |
New compounds of 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid ester type having general formula I wherein R is a lower alkyl group, which is methyl or ethyl R1 and R2 is sodium carboxylate-methyl ester, having synergistic cytotoxic effect combined with 5-fluorouracil. |
| 申请公布号 |
US2012022088(A1) |
申请公布日期 |
2012.01.26 |
| 申请号 |
US201013138614 |
申请日期 |
2010.03.11 |
| 申请人 |
DUBURS GUNARS;BISENIEKS EGILS;SESTAKOVA IRINA;KALVINSH IVARS;VIGANTE BRIGITA;ULDRIKIS JANIS;DOMRACEVA ILONA;JASCENKO ELINA;POIKANS JANIS;BRUVERE IMANTA;STONANS ILMARS;JSC GRINDEKS |
发明人 |
DUBURS GUNARS;BISENIEKS EGILS;SESTAKOVA IRINA;KALVINSH IVARS;VIGANTE BRIGITA;ULDRIKIS JANIS;DOMRACEVA ILONA;JASCENKO ELINA;POIKANS JANIS;BRUVERE IMANTA;STONANS ILMARS |
| 分类号 |
A61K31/44;A61K31/513;A61P35/00;C07D213/80 |
主分类号 |
A61K31/44 |
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