XYXIN FRAGMENT BIOMARKER FOR DIAGNOSIS OF COLON CANCER

摘要

The present invention relates to the field of the diagnosis of large intestine/colon diseases. More particularly, the present invention provides a method for differential diagnosis of colorectal cancer from a non-malignant disease of the large intestine/colon, and from a healthy large intestine/colon. The invention also relates to treatment of colorectal cancer. The peptide fragment, consisting of amino acids 62 to 110 of human Xyxin, was found to be significantly down regulated in serum samples obtained from colorectal cancer populations, as compared to serum samples obtained from healthy control populations and benign disease populations.