<p>The present invention relates to a process for preparing a short oligonucleotide comprising the steps of: (i) preparing a crude mixture comprising the oligonucleotide (ii) subjecting the mixture formed in step (i) to a desalting step; wherein the process does not comprise a chromatographic purification step.</p>
申请公布号
WO2012010711(A1)
申请公布日期
2012.01.26
申请号
WO2011EP62707
申请日期
2011.07.25
申请人
SANTARIS PHARMA A/S;MELDGAARD, MICHAEL;MOGENSEN, MARIANNE;FRAUENDORF, CHRISTIAN;ROSENBOHM, CHRISTOPH
发明人
MELDGAARD, MICHAEL;MOGENSEN, MARIANNE;FRAUENDORF, CHRISTIAN;ROSENBOHM, CHRISTOPH