Methods are provided for diagnosis and prognosis of disease by analyzing expression of a set of genes obtained from single cell analysis. Classification allows optimization of treatment, and determination of whether on whether to proceed with a specific therapy, and how to optimize dose, choice of treatment, and the like. Single cell analysis also provides for the identification and development of therapies which target mutations and/or pathways in disease-state cells.
申请公布号
CA2806632(A1)
申请公布日期
2012.01.26
申请号
CA20112806632
申请日期
2011.07.19
申请人
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
发明人
CLARKE, MICHAEL F.;QUAKE, STEPHEN R.;DALERBA, PIERO D.;LIU, HUIPING;LEYRAT, ANNE;KALISKY, TOMER;DIEHN, MAXIMILIAN;ROTHENBERG, MICHAEL;WANG, JIANBIN;LOBO, NEETHAN