PHARMACEUTICAL DEPOT FOR 5-FLUORO-2 [ [ (1S) -1- (5-FLUORO-2-PYRIDYL)ETHYL]AMINO]-6-[(5-ISOPROPOXY-1H-PYRAZOL-3-YL)AMINO]PYRIDINE-3-CARBONITRILE
摘要
A pharmaceutical depot comprising (i) 5-fluoro-2-[[(1S)-1-(5-fluoro-2- pyridyl)ethyl]amino]-6-[(5-isopropoxy-1H-pyrazol-3-yl)amino]pyridine-3-carbonitrile, or a pharmaceutically-acceptable salt thereof, as a pharmaceutical agent (PA) and (ii) a polymer which degrades to create an acidic microclimate, wherein the PA is released from the polymer upon polymer degradation.
申请公布号
WO2012010883(A2)
申请公布日期
2012.01.26
申请号
WO2011GB51357
申请日期
2011.07.19
申请人
ASTRAZENECA AB;FULLER, EMILY;JANIN, ARMELLE;MACFAUL, PHILIP;PUGH, RACHEL;NASH, IAN
发明人
FULLER, EMILY;JANIN, ARMELLE;MACFAUL, PHILIP;PUGH, RACHEL;NASH, IAN