发明名称 TRICYCLIC CONDENSED HETEROCYCLIC COMPOUND, PROCESS OF PRODUCING SAME, AND USE THEREOF
摘要 A novel compound derived from the culture product of an actinomycete and having an antitumor activity is provided. Provided is a compound represented by any one of formulas (I), (II) and (III) or an optical isomer thereof or a pharmaceutically acceptable salt thereof which can be isolated from the culture fluid of an actinomycete which belongs to the genus Streptomyces, wherein R1, R2, R5 and R6 each independently represent a hydrogen atom, a methyl group, a hydroxymethyl group, a hydroxyl group, or a double bond by which R1 and R2 or R5 and R6 are bonded; R3, R4, R7 and R8 each independently represent a methyl group or a hydroxymethyl group; and R9 represents a hydrogen atom or a hydroxyl group.
申请公布号 US2012022153(A1) 申请公布日期 2012.01.26
申请号 US201013259227 申请日期 2010.03.24
申请人 SATO SEIZO;IWATA FUMIE;YAMADA SHOICHI;TAKEO JIRO;ABE AKIHISA;KAWAHARA HIROYUKI;NIPPON SUISAN KAISHA, LTD. 发明人 SATO SEIZO;IWATA FUMIE;YAMADA SHOICHI;TAKEO JIRO;ABE AKIHISA;KAWAHARA HIROYUKI
分类号 A61K31/343;A61P35/00;C07D307/93;C12P17/04 主分类号 A61K31/343
代理机构 代理人
主权项
地址