| 摘要 |
A class of macrocyclic compounds of formula (I), wherein R1, R3, R4, Ra, Rb, A, B, Z, M, W and n are defined herein, that are useful as inhibitors of viral proteases, particularly the hepatitis C virus (HCV) NS3 protease, are provided. Also provided are processes for the synthesis and use of such macrocyclic compounds for treating or preventing HCV infection. |
| 申请人 |
MERCK SHARP & DOHME CORP.;ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE S.P.A. |
发明人 |
MCCAULEY, JOHN, A.;LIVERTON, NIGEL, J.;HARPER, STEVEN;MCINTYRE, CHARLES, A.;RUDD, MICHAEL, T. |
