发明名称 OXAZOLOPYRIMIDINES AS EDG-1 RECEPTOR AGONISTS
摘要 The present invention relates to oxazolopyrimidine compounds of the formula I, in which A, R 1 , R 2 and R 3 are defined as indicated in the claims. The compounds of the formula I modulate the activity of the Edg-1 receptor and in particular are agonists of this receptor, and are useful for the treatment of diseases such as atherosclerosis, heart failure or peripheral arterial occlusive disease, for example. The invention furthermore relates to processes for the preparation of compounds of the formula I, their use, in particular as active ingredients in pharmaceuticals, and pharmaceutical compositions comprising them.
申请公布号 ZA201008786(B) 申请公布日期 2012.01.25
申请号 ZA20100008786 申请日期 2010.12.07
申请人 SANOFI-AVENTIS 发明人 KADEREIT DIETER;SCHAEFER MATTHIAS;CZECHTIZKY WERNGARD
分类号 A61K;A61P;C07D 主分类号 A61K
代理机构 代理人
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