发明名称 17-HYDROXY-19-NOR-21-CARBOXYLIC ACID-STEROID Y-LACTONE DERIVATIVE,USE THEREOF,AND MEDICAMENT CONTAINING THE DERIVATIVE
摘要 The invention relates to 17-hydroxy-19-nor-21-carboxylic acid-steroid γ-lactone derivatives with the chemical formula I, where R4, R6a, R6b, R7, R15, R16a, R16b, R18 and Z have the meanings stated in claim 1, and their solvates, hydrates, stereoisomers and salts. The invention further relates to the use of these derivatives for the production of a medicinal product for oral contraception and for the treatment of pre-, peri- and postmenopausal complaints and medicinal products that contain said derivatives. The derivatives according to the invention have a progestational and in preferred cases additionally an antimineralocorticoid and neutral to slightly androgenic action.
申请公布号 ZA201005396(B) 申请公布日期 2012.01.25
申请号 ZA20100005396 申请日期 2010.07.28
申请人 BAYER PHARMA AG 发明人 KLAR ULRICH;KUHNKE JOACHIM;BOHLMANN ROLF;HUBNER JAN;RING SVEN;FRENZEL THOMAS;MENGES FREDERIK;BORDEN STEFFEN;MUHN HANS-PETER;PRELLE KATJA
分类号 A61K;A61P;C07J 主分类号 A61K
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