Multi-channel reagent dispensing apparatus and dispensing method

摘要

Embodiments of the present invention are directed to an improved chemical synthesis apparatus for performing chemical synthesis such as nuclei acid synthesis in a plurality of reaction wells or cells in an efficient manner. The apparatus employs dispenser heads (16) that each include a cluster of nozzles (14) which are fluidicly coupled to a plurality of reagent sources (12) for dispensing different reagents through the single dispenser head. Because each dispenser head (16) is capable of dispensing a plurality of different reagents, the apparatus can perform simultaneous synthesis in a plurality of cells at a high throughput without complex and elaborate control of movement of the dispenser heads (16) relative to the cells.