发明名称 |
GPR119 receptor agonists in methods of increasing bone mass and of treating osteoporosis and other conditions characterized by low bone mass, and combination therapy relating thereto |
摘要 |
The present invention relates to the use of GPR119 receptor agonists for treating or preventing a condition characterized by low bone mass, such as osteoporosis, and for increasing bone mass in an individual. The present invention further relates to the use of a GPR119 receptor agonist in combination with a dipeptidyl peptidase IV (DPP-IV) inhibitor for treating or preventing a condition characterized by low bone mass, such as osteoporosis, and for increasing bone mass in an individual. A GPR119 receptor agonist and the combination of a GPR119 receptor agonist and a DPP-IV inhibitor promote bone formation in an individual. |
申请公布号 |
US8101626(B2) |
申请公布日期 |
2012.01.24 |
申请号 |
US20100752671 |
申请日期 |
2010.04.01 |
申请人 |
CHU ZHI-LIANG;LEONARD JAMES N.;LEHMANN JUERG;JONES ROBERT M.;ARENA PHARMACEUTICALS, INC. |
发明人 |
CHU ZHI-LIANG;LEONARD JAMES N.;LEHMANN JUERG;JONES ROBERT M. |
分类号 |
A61K31/69;A61K31/277;A61K31/40;A61K31/403;A61K31/426;A61K31/4985 |
主分类号 |
A61K31/69 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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