发明名称 |
Calcium blockers to treat proliferative vitreoretinopathy |
摘要 |
Glutamate causes migration and proliferation of retinal pigment epithelium and/or glial cells, and glutamate antagonists can prevent, treat or reduce retinal pigment epithelium and/or glial migration and the subsequent development of proliferative vitreoretinopathy. Avoidance or management of proliferative vitreoretinopathy can be achieved by administering to the patient a compound capable of reducing glutamate-induced retinal cell migration in a concentration effective to reduce such migration.
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申请公布号 |
US8101635(B2) |
申请公布日期 |
2012.01.24 |
申请号 |
US20040885422 |
申请日期 |
2004.07.06 |
申请人 |
DREYER EVAN B.;ALLERGAN, INC. |
发明人 |
DREYER EVAN B. |
分类号 |
A61K31/445;A61K45/00;A61K31/00;A61K31/135;A61K31/44;A61P27/02;A61P43/00 |
主分类号 |
A61K31/445 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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