发明名称 |
Artemisinic epoxide and methods for producing same |
摘要 |
The present invention provides artemisinic epoxide, and methods of synthesizing artemisinic epoxide in a genetically modified host cell. The present invention further provides methods for producing artemisinin. The present invention further provides variant enzymes that catalyze the oxidation of amorpha-4,11-diene to artemisinic epoxide; nucleic acids encoding the variant enzymes; as well as recombinant vectors and host cells comprising the nucleic acids. |
申请公布号 |
US8101399(B2) |
申请公布日期 |
2012.01.24 |
申请号 |
US20070955154 |
申请日期 |
2007.12.12 |
申请人 |
DIETRICH JEFFREY ALLEN;YOSHIKUNI YASUO;KEASLING JAY D.;CHANG MICHELLE CHIA-YU;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
DIETRICH JEFFREY ALLEN;YOSHIKUNI YASUO;KEASLING JAY D.;CHANG MICHELLE CHIA-YU |
分类号 |
C12N1/00;C12N1/19;C12N1/20;C12N1/21 |
主分类号 |
C12N1/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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