发明名称 |
Process for the manufacturing of the compound 2-hydroxy-3-[5-(morpholin-4-ylmethyl)pyridin-2-yl]1H-indole-5-carbonitrile 701 |
摘要 |
The present invention relates to a new process for the manufacture of the compound 2-hydroxy-3-[5-(morpholin-4-ylmethyl)pyridin-2-yl]1H-indole-5-carbonitrile as a free base and pharmaceutically acceptable salts thereof, particularly the 2-hydroxy-3-[5-(morpholin-4-ylmethyl)pyridin-2-yl]1H-indole-5-carbonitrile citrate, and to new intermediates prepared in said process suitable for large scale manufacturing of said compound. |
申请公布号 |
US8101750(B2) |
申请公布日期 |
2012.01.24 |
申请号 |
US20080596020 |
申请日期 |
2008.04.17 |
申请人 |
DELISSER VERN;HEDBERG MARTIN;JANSSON ANNETTE;RAADEVIK ANDREAS;RYBERG PER;THIERING SWANTJE;ASTRAZENECA AB |
发明人 |
DELISSER VERN;HEDBERG MARTIN;JANSSON ANNETTE;RAADEVIK ANDREAS;RYBERG PER;THIERING SWANTJE |
分类号 |
C07D295/16 |
主分类号 |
C07D295/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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