发明名称 |
USE OF COMPOUNDS THAT REDUCE ALPHA2-ANTIPLASMIN IN VIVO FOR THE PREPARATION OF A COMPOSITION FOR THE TREATMENT OF ISCHEMIC STROKE |
摘要 |
The present invention relates to a new means for the treatment of focal ischemic cerebral infarction (ischemic stroke). It has been found that reduction of .alpha.2-antiplasmin leads to a significantly smaller focal cerebral infarct size. The invention therefore provides the use of compounds that reduce .alpha.2-antiplasmin concentration or activity in vivo, for the preparation of a therapeutical composition for the treatment of focal cerebral ischemic infarction (ischemic stroke).
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申请公布号 |
CA2344317(C) |
申请公布日期 |
2012.01.24 |
申请号 |
CA19992344317 |
申请日期 |
1999.09.24 |
申请人 |
LEUVEN RESEARCH & DEVELOPMENT VZW |
发明人 |
NAGAI, NOBUO;COLLEN, DESIRE JOSE |
分类号 |
A61K39/395;A61K45/00;A61K38/00;A61K38/48;A61P7/02;A61P9/08;A61P9/10;C07K16/38 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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