发明名称 |
MIRAC PROTEINS. |
摘要 |
This disclosure relates to a method of generating conditionally active biologic proteins from wild type proteins, in particular therapeutic proteins, which are reversibly or irreversibly inactivated at the wild type normal physiological conditions. For example, evolved proteins are virtually inactive at body temperature, but are active at lower temperatures. |
申请公布号 |
MX2011009422(A) |
申请公布日期 |
2012.01.20 |
申请号 |
MX20110009422 |
申请日期 |
2010.03.09 |
申请人 |
BIOATLA, LLC |
发明人 |
SHORT, JAY, M.;CHANG, HWAI WEN;FREY, GERHARD;FROST, GREGORY |
分类号 |
C12Q1/68;A61K38/17;C07K14/00;C12P21/00 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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