METHOD AND RELATED DEVICES FOR MIXING TWO INJECTABLE COMPOSITIONS PRIOR TO INJECTION

摘要

This invention relates to a method for mixing a first injectable liquid pharmaceutical composition and a second injectable composition within an injection device, said injection device including: ° a generally cylindrical shell in which a cartridge is lodged or a generally cylindrical barrel, ° at one first end of the generally cylindrical barrel or the generally cylindrical shell, a plunger, the plunger being mounted on the barrel or shell, ° at a second end opposite the first end of the generally cylindrical barrel or the generally cylindrical shell, is provided a needle assembly support member, on which may be mounted a needle assembly, said needle assembly comprising means to be mounted on the needle support member, and further comprising: - at least one hollow cannula for transportation of liquid from the barrel or cartridge to the body of the patient; - and at least one hub surrounding part of the cannula and attached to cannula; said hub possibly including a hollow part; characterized in that the first injectable composition is within the cylindrical barrel or within the cartridge lodged in the cylindrical shell and the second injectable composition is associated with the needle assembly, and further characterized in that the mixture of said first and said second composition occurs in the hub, in the cartridge, or in the cannula or the barrel. The invention also relates to said needle assembly and to said injection device.