| 发明名称 |
PYRIDINE COMPOUNDS AS SODIUM CHANNEL BLOCKERS |
| 摘要 |
<p>The invention relates to substituted pyridine compounds of Formula I: (I) or a pharmaceutically acceptable salt, prodrug, or solvate thereof, wherein A1, X, A2, R1a, R1b, R1c, G, and z are defined as set forth in the specification. The invention is also directed to the use of compounds of Formula I to treat a disorder responsive to the blockade of sodium channels. Compounds of the present invention are especially useful for treating pain.</p> |
| 申请公布号 |
WO2012007836(A1) |
申请公布日期 |
2012.01.19 |
| 申请号 |
WO2011IB01705 |
申请日期 |
2011.07.15 |
| 申请人 |
PURDUE PHARMA .LP.;KYLE, DONALD, J.;NI, CHIYOU;PARK, MINNIE;TAFESSE, LAYKEA |
发明人 |
KYLE, DONALD, J.;NI, CHIYOU;PARK, MINNIE;TAFESSE, LAYKEA |
| 分类号 |
C07D213/81;A61K31/4412;A61K31/443;A61K31/4439;A61K31/444;A61P25/00;C07D401/12;C07D413/12 |
主分类号 |
C07D213/81 |
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