PAPILLOMA VIRUS-LIKE PARTICLE, FUSION PROTEIN AS WELL AS PROCESS FOR THEIR PRODUCTION

摘要

PROBLEM TO BE SOLVED: To provide recombinantly produced proteins as well as VLPs which are suitable as a vaccine for therapeutic and prophylactic vaccination, and to make available methods for the production of these proteins and VLPs.

SOLUTION: In recombinantly produced papilloma virus-like particles which are formed after expression of the viral structural proteins L1 and/or L2, the papilloma virus-like particles has a remained ability of forming virus-like particles by deleting one or multiple sections of the L1 and/or L2 protein.

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